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Additionally, rare loss-of-function germline mutations of Kelch-like ECH-associated protein 1 (KEAP1) could be detected in nodular goitre leading to Nrf2 pathway activation that favours transcription of cytoprotective and antioxidant enzymes (92)

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and Bordetella bronciseptica

Change history 28 October 2014 This paper was modified 12 months after initial publication to switch to Creative Commons licence terms, as noted at publication References Armstrong AJ, Garrett-Mayer E, Ou Yang YC, Carducci MA, Tannock I, de Wit R, Eisenberger M (2007) Prostate-specific antigen and pain surrogacy analysis in metastatic hormone-refractory prostate cancer