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The experiments were approved by the Local Ethics Committee

Consistent technique matters more than perfect technique

Also, the sphincter failure results from other agents with either apparently less gastrointestinal toxicity, i.e., celecoxib (12, 50), or without gastrointestinal lesions (i.e., paracetamol) (3, 8)

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents: To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions