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Hypothyroidism has been shown to be linked to autoimmunity in 95% of cases

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Results Effects of TLYY administration on body weight and pathological features in DSS-induced mice The DSS-induced colitis mouse model closely recapitulates the symptomatic manifestations of human ulcerative colitis, including reduced activity, body weight loss, diarrhea, and fecal occult blood

It also prevents proteolytic clearance of amyloid by blocking the activity of enzymes crucial for the process (Cook et al., 2003