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Several of these diseases disrupt organogenesis as well, and can lead to significant congenital anomalies and mental retardation

The CRH signaling is schematically represented in Figure 13 , and comprehensive details of SAM/epinephrine signaling are described in the Supplementary Data

The hyperphosphorylated tau protein was elevated in the cortical and hippocampal neurons of MSG-treated mice, and the cerebral cortex displayed symptoms of neurodegeneration, including spongiosis of the neuropil, widespread vacuolation, and disorganized cortical laminae

Obesity is an independent risk factor for plasma lipid peroxidation and depletion of erythrocyte cytoprotectic enzymes in humans