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The biology is straightforward: THC is fat-soluble, gets stored in adipose tissue, and metabolizes slowly over days to months depending on your frequency of use, body composition, and individual metabolism

Authors of a 2022 systematic review on e-cigarettes and weight gain highlight this issue, noting, Smoking cessation is associated with a mean increase of four to five kilograms in body weight after 12 months of abstinence, and most weight gain occurs within three months of quitting. (This kilogram range equates to eight to 11 pounds.) The appeal of vaping can be attributed to nicotine, a common component in both traditional cigarettes and most vaping products, known for its appetite-suppressing effects

Individual studies have reported that smoking only one to five cigarettes per day is associated with a higher than expected risk of heart disease

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