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Matsuzaki et al., 2010)

5 Conclusion Kinetic modeling and Metabolic Control Analysis allowed the identification of complex I as a promising target for developing therapeutic strategies to selectively inhibit cancer cell proliferation due to its higher flux control on the Krebs Cycle pathway

Peer review Peer review information Nature Reviews Gastroenterology & Hepatology thanks Gionata Fiorino, Alessandro Armuzzi, Giuseppe Privitera and the other, anonymous, reviewer(s) for their contribution to the peer review of this work