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Moreover, advanced glycation end products-receptor accumulation were nearly reversed to the normal levels along with inhibition of AGE-RAGE expression in STZ-treated diabetic rat by DAP ( The Ophiopogon japonicus polysaccharide (OJP) exhibited antioxidant effects by efficiently diminishing the levels of free radicals (DPPH and ABTS), markedly enhancing the NO production, and diminishing the mRNA expressions of iNOS, COX2 in nickel-induced RAW264.7 cells ( The polysaccharide isolated from Rehmannia glutinosa (RGP), as a main active ingredient exhibited hypoglycemic effects (Zhou et al., 2015a)

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Therefore, it is important to consider product quality, clinic credibility, and always consult a qualified medical professional before use to ensure safety and suitability

10.1016/j.biopha.2022.112957 42 HuaX.FengX.HuaY.WangD