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[199] Misfolded SOD1 binding, however, triggers conformational change in Bcl2 that exposes its toxic BH3 domain, triggering cytochrome c release and apoptosis.[ 197b , 198 ] Further, misfolded SOD1/Bcl2 complexes are suggested to reduce outer mitochondrial membrane permeability by directly inhibiting voltagedependent anion channel 1, [200] an outer mitochondrial membrane porin regulating mitochondrial ATP production and export

Most people get enough lysine from foods in their diet including red meat, cheese, fish, and eggs, but "athletes, burn patients, and vegans who do not eat beans may need more," according to Mount Sinai

Shusharina N, Liao Z, Mohan R , Choi N, Bortfeld T

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