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PloS One (2013) 8:e66019

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Because the flanking normal splice site remains, both normal and abnormal splicing occurs and some normal -globin mRNA is made, resulting in + -thalassemia

Acknowledgements The authors wish to acknowledge grant support from the German Research Foundation (DFG), Clinical Research Unit KFO 181, projects 1 (STE 892/9-2) and 6 (SCHA 1531/1-1)