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Induction of arginase I transcription by IL-4 requires a composite DNA response element for STAT6 and C/EBP

& Kollman J

They are rarely tested in large human studies, and small short-term studies do not provide strong evidence 16

The JAK/STAT signaling pathway, as the main target for inhibiting the action of a variety of cytokines (221), is involved in the signal transduction of many key cytokines for the pathogenesis of RA and has been considered as a potential target for the treatment of RA (222)