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In contrast, the knockout of tier-2 targets inhibits viral replication and impacts normal cellular metabolism

doi: 10.3389/fnut.2023.1143682 Received 13 January 2023 Accepted 03 April 2023 Published 05 May 2023 Volume 10 - 2023 Edited by Changling Hu, North Carolina Agricultural and Technical State University, United States Reviewed by Haibo Dong, University of North Carolina at Greensboro, United States

The association of the genetic variants in the genes encoding GSTs, especially GSTM1 cluster, with cardiac problem, such as coronary artery disease, ischemic heart disease or heart failure were described in several GWAS across different populations worldwide [89,90,91,92]