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This pace was enabled by several factors: the strength and consistency of the Phase 2 efficacy signals, Eli Lilly's extensive infrastructure for metabolic disease trials built through the tirzepatide program, the availability of well-characterized biomarkers and endpoints for obesity and diabetes, and the increasing regulatory receptivity to obesity treatments as the field matured

Sterile syringes and needles should be used for each injection, and proper aseptic technique must be observed to avoid introducing bacteria or other pathogens