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However, the proliferation and antiviral responses of Scap knockout CD8 + T cells are significantly impaired, accompanied by reduced nutrient uptake, glycolysis, and mitochondrial oxidative phosphorylation

This pro-drug is used to treat SLE, specifically LN, due to the immunosuppressive activity

Despite these developments, there remains a gap in comprehensive reviews that address epigenetic regulations in physiological and disease contexts and detail the latest advancements in drug development targeting these mechanisms