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Modern-day leech therapy is rare and typically limited to specific medical applications rather than general detoxification

Expression of IGF in primates and rodents Based on previous findings, the FSH as an essential agent has a role to generate the follicles (before ovulation) and differentiate the granulosa cells, but the presence of FSH alone is not enough, and other factors are necessary for growth and differentiation

On the other hand, the nuclear factor-erythroid factor 2-related factor 2 (Nrf2)/heme oxygenase (HO-1) signaling pathway is essential for controlling the antioxidant and anti-inflammatory qualities of natural products that contain bioactive substances