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More rarely, more serious reactions may occur, such as allergic reactions (urticaria, itching, shortness of breath, facial swelling), heart failure in people with pre-existing problems, or hypokalemia (low potassium levels) at the beginning of treatment due to increased hematopoiesis

They are also FDA-approved, a fact which validates the fact that these substances are proven to be safe for their intended purpose as facial fillers

5 Improving mood: Vitamin B12 is involved in producing neurotransmitters, such as serotonin and dopamine, which are important for mood regulation

Fraser et al, however, reported no resistance by patients to reducing the frequency of their injections