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Their prophylactic excision is not justified.8,27 AMS has already been described by several authors and institutions based on clinical characteristics of patients and their personal and/or family history of melanoma, with or without histopathological confirmation of an atypical nevus.3 According to Newton et al.1, AMS can be defined through a scoring system, assigning one point for each feature, as seen in Table 1

"If you don't know what you're taking, you should probably avoid it," Prof Tony Cass says

Understanding these differences can help researchers select the most appropriate compound for their investigative goals

differential diagnosis of genital pigmented lesions has a wide range spectrum like melanosis, melanocytic nevi, seborrheic keratosis, basal cell carcinoma, other diseases such as post-inflammatory hyperpigmentation, lichen planus, Bowens disease, Bowenoid papulosis and most importantly melanoma