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Local reactions may include erythema, pruritus, induration, or mild pain at the injection site, potentially affecting five to ten percent of patients

As an RD, there are generally three situations where I believe runners should consider a Vitamin B12 supplement: If your blood work has shown a Vitamin B12 deficiency* If you follow plant-based diet (especially strict vegan diets)* If you notice you dont eat many B12-rich foods* Keep in mind that deficiencies can happen even if you are eating a variety of B12-rich foods