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62 Oxidative stress Oxidative stress is a condition that results in the production of ROS or reactive nitrogen species (RNS) that cannot be adequately addressed by normal antioxidant mechanisms

Curcumin reduced H2O2-and G2385R-LRRK2-induced neurodegeneration

[3] They can inhibit oxidizing chain reactions in several ways, including direct quenching of reactive oxygen species, inhibition of enzymes, and chelation of metal ions (Fe3+, Cu+)

We observed neither an NMD-dependent increase in general HIF-1 activity nor a hif-1- dependent increase in NMD activity, indicating that neither NMD nor HIF-1 acts strictly upstream of the other