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References Deumer US, Varesi A, Floris V, et al

Blood (2021) 138(10):87184

For example, in Hordeum vulgare leaves challenged with the powdery mildew fungus, Blumeria graminis , the fungal infection led to a significant decrease in APX and GR activity in whole-leaf extracts of resistant variety but caused no significant change in the susceptible one

PEO can also be attributed to multiple mtDNA deletions or depletion, secondary to nDNA mutations, which follow either autosomal recessive or dominant inheritance patterns and involve genes such as POLG, POLG2, SLC25A4, C10orf2, SPG7, DNA2, RNASEH1, TOP3A, TK2, DGUOK, RRM2B, GMPR, LIG3 , and RRM1