Clinical and Research Dosing Phase 3 Clinical Trial Dose: The standard dose used in Phase 3 trials for PMM and Heart Failure research is 40 mg SubQ once daily
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This contributes to the occurrence of l-dopa-related complications (LDRCs), notably motor fluctuations and l-dopa-induced dyskinesia, whose severity is associated with nigral denervation 2,3,4,5,6,7,8,9