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Incubation of acetone with homogenates of nasal mucosa from mice indicated that acetone was metabolized via a NADPH-dependent pathway in vitro , but no evidence of in vivo metabolism of acetone by the upper respiratory tract was found in mice, rats, guinea-pigs or hamsters (Morris, 1991 )

The sequence variability is uniformly and equally distributed throughout the viral genome

Outside the CNS, serotonin is produced in the ENS and released predominantly by enterochromaffin cells (estimated to be up to 90% of the body's serotonin production [169]) of the gut mucosa and immune cells, with influence not only on the ENS but also on the CNS via the GBA [283]