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The resulting plasmids, pYES2-AsGGT1, pYES2-AsGGT2, and pYES2-AsGGT3, and pYES2 empty vector were transformed into the Saccharomyces cerevisiae mutant strain BJ2168 ( MATa, prb1-1122, prc1-407, pep4-3, ura3-52, leu2, trp1

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10.1146/annurev.cb.04.110188.001445 Annu

Loss of Kelch-like ECH-associated protein 1 function in prostate cancer cells causes chemoresistance and radioresistance and promotes tumor growth