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Description

Tricarboxylic acid cycle (TCA)-associated metabolisms were the main metabolic pathways reprogramed during establishment and passage of patient-derived xenograft model By using relative quantitative metabolites enrichment analysis and metabolic pathway analysis, we found glycolysis/gluconeogenesis, TCA metabolism and TCA-associated metabolic replenishment pathways were highly associated with the metabolomic difference of PC vs

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& Reis, F

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Variants such as MTHFR C677T can raise homocysteine and increase functional demand on the B12 pathway

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Materials and Methods Granzymes GrK and GrKSA were produced as described previously (25)

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