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In the cytosol, formate is converted to 10-formyl-THF and subsequently to 5,10-methylene-THF, completing a redox cycle

Moreover, the TP53 mutation was found in all ERBB4-mutated patients of the both cohorts

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Article contents Abstract Physiological changes in pregnancy affecting B-vitamin biomarkers B-vitamin biomarkers during pregnancy Recommendations for B-vitamin intake in pregnancy Clinical implications of B-vitamins in pregnancy Conclusions Ethics of human subject participation Financial support Conflicts of interest Authorship References B-vitamins and one-carbon metabolism during pregnancy: health impacts and challenges Published online by Cambridge University Press: 23 September 2024 Abstract Physiological changes in pregnancy affecting B-vitamin biomarkers B-vitamin biomarkers during pregnancy Recommendations for B-vitamin intake in pregnancy Clinical implications of B-vitamins in pregnancy Conclusions Ethics of human subject participation Financial support Conflicts of interest Authorship References Abstract Folate, vitamin B12, vitamin B6 and riboflavin interact by functioning as cofactors within one-carbon metabolism (OCM), a network of interrelated cellular pathways essential for numerous biological processes, including the biosynthesis of DNA, amino acid interconversions and methylation reactions