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Description

Ballatori et al., 2005

SCI induces ferroptosis of vascular endothelial cells and destroys the integrity of the blood-spinal cord barrier

The limitations of the current study include the lack of critically ill ventilated ICU patients (as participants had to be able to provide consent), the lack of multiple longitudinal sampling and small sample size

Concurrently, enhanced KP activity depletes TRP availability for 5-HT synthesis, weakening serotonergic inhibition of the amygdala, which in turn facilitates HPA axis activation [134]