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This possibility has been directly assessed by Kim et al, 2008 [77] who used a knock-in mouse model in which wild-type MORs were replaced with a mutant receptor capable of undergoing rapid morphine-dependent sequestration [27]

These tumorigenic cells are like adult or embryonic stem cells in their ability to self-renew and give rise to a diversity of cells that differentiate and after a finite number of divisions, eventually succumb to programmed cell death

Data on new-generation amylin analogs Among the companies developing amylin analogs, Novo Nordisk, the pioneer of GLP-1s, is furthest along

Hyperthermie, flexikon.doccheck.com (Abruf: 14.12.2020) Hitzschlag und Sonnenstich, www.amboss.com (Abruf: 10.2.2021) There is no universally defined threshold temperature and it varies according to the literature