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We also demonstrate a novel method for creating glutathione-laden PEGDA microspheres using reverse-phase emulsion polymerization

However, another study using a comparable model reported elevated cytokine and oxidative stress markers in the cortex and hippocampus without detectable changes in neurogenesis ( 6 Mechanisms of chronic stress-induced neuronal dysfunction 6.1 Neuroinflammation Neuroinflammation refers to immune activation and inflammatory responses within the central nervous system (CNS), typically involving sustained activation of microglia and astrocytes as well as excessive release of proinflammatory cytokines (Sotzny et al., 2018), increased numbers of activated CD8 + cytotoxic T cells (Rivas et al., 2018), and elevated levels of multiple proinflammatory cytokines (Montoya et al., 2017)

The authors claimed that MSG is the silent killer of various organs of animal models and human. However, glutamate is a nonessential amino acid and an essential substrate for protein synthesis

doi: 10.1073/pnas.1005225107 88 ZhaoH