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smegmatis growth and the inhibitors target actually another system than the one originally supposed

Alcohol directly activates GIRK channels through a physical alcohol pocket in GIRK channels Ethanol exerts diverse effects on both the central nervous system (CNS) and peripheral organs, leading to CNS depression, intoxication, addiction, cardiac arrhythmia, and hepatic and pancreatic dysfunctions (Peoples et al., 1996)