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Contrary to the classic definition of a vitamin, researchers recently submitted the idea that since ERGO is commonly found in small amounts in nearly all foods but may not be present in sufficient amounts for optimum long-term health, it possibly could be considered as a vitamin (Reference Borodina, Kenny and McCarthy28)

Schroeder GK, Johnson WH, Huddleston JP, Serrano H, Johnson KA, Whitman CP (2012) Reaction of cis3-chloroacrylic acid dehalogenase with an allene substrate, 2,3-butadienoate: hydration via an enamine

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This study of hospitalized ICU patients with severe sepsis or septic shock was limited by its small size (n=79) and the frequent rate of clinician over-rule of the study algorithm in the per protocol procalcitonin-arm patients (6/31, or 19% of patients) [15]