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Proline is catalyzed by proline dehydrogenase enzyme (PRODH) to generate glutamate, which enters the TCA cycle to generate ATP and provides energy support for the activation of DCs and antigen presentation

Mohan Rema, Mohan V, Bhaskar A, Shanmugasundaram KR (1995) Does oxidant stress play a role in diabetic retinopathy

The Wells score is determined by major risk factors (recent history of surgery or bed rest, immobilization, or presence of cancer), physical exam findings (edema, engorgement, enlargement, tenderness, and superficial vein dilation in the affected limb), and history (previous DVT and absence of another likely explanation for signs and symptoms)