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LDEVs have been shown to activate the aryl hydrocarbon receptor (AhR)/ Nrf2 pathway in human dermal fibroblasts, leading to reduced ROS production and enhanced cellular resistance to oxidative injury [166]

we don't know how many traits that 'rejuvenation' involves

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The study called for further investigation of glutathione levels in a larger sample size to differentiate the potential association by manic or depressive episodes, as well as the use of N-acetyl-L-cysteine (NAC) which the body converts into cysteine and then glutathione as therapeutic agent for suicide risk intervention