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Description

Astrocyte crosstalk in CNS inflammation

Nature 529:216220

TTD: Therapeutic target database

In accordance, morphological and functional alterations, such as the impaired activity of complex-III of the mitochondrial respiratory chain, were found in the brains of AS model mice [8, 10, 12], and restoring the expression of complexes III and IV by CoQ10 analog ameliorates motor coordination, obsessive-compulsive behavior, and anxiety deficits in AS mice [11]