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doi: 10.9758/cpn.2015.13.2.188

In addition, CB-839 has been extensively studied in hematological malignancies such as acute myeloid leukemia (AML) (Okabe et al., 2022), and multiple myeloma (MM) ( TABLE 2 Clinical trials on targeting glutamine metabolism

Reported side effects are typically mildsuch as injection-site irritation, headache, or fatiguebut regulatory reviews highlight potential immunogenicity and uncertainties around long-term safety and product quality in compounded or nonapproved forms