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4 BertoloneL.RoyM

The early appearance of non-motor symptoms, years before overt motor signs emerge, implies that early glial involvement, particularly microglia-driven ferroptosis, may serve as a critical initiating event

Maes M, Yirmyia R, Noraberg J, Brene S, Hibbeln J, Perini G, Kubera M, Bob P, Lerer B, Maj M

Through this process, tumor cells exhibit higher migratory and invasive ability, poorer outcomes, and increased resistance to various treatments (Li et al., 2015)