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Targeting VEGF has dramatically improved the management of many diseases like blinding eye diseases such as age-related macular degeneration and diabetic and hypertensive retinopathy and shows promising data in cancer treatment [11]

Based on these findings, the authors concluded that assessment of liver enzymes could identify individuals at a high risk of incident T2D who may benefit from T2D prevention interventions

Disadvantages are: not FDA-approved for women, reversibly raising liver tests (need to monitor every 3 months)