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Similarly, tubulin acetylation and total lysine acetylation dynamics, as assessed by a pan K-ac antibody, were comparable between genotypes (Figure 4D

FLS are predominant cells of the synovium and contribute to inflammatory and metabolic changes during joint diseases 22,35

Future research should further explore the dynamic changes in immune cell subsets, the interaction mechanisms between immune cells and chondrocytes, and the feasibility of combination therapy strategies

Therefore, even though B12 may come in more concentrated dosages with oral administration, the IM shots still provide the best way to correct B12 deficiency