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However, the complexity could also provide an opportunity for drug development, as many cellular alterations in PD (and other neurodegenerative disease for that matter) can be modulated by alleviating mitochondrial dysfunction

Acknowledgments The authors would like to thank tefan Rac for technical assistance in EEG recordings and Eva Rihar, MD for help with patient enrollment

The n-3 and n-6 series are closely related to the human health, the n-3 series include alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), the n-6 series mainly include linoleic acid and arachidonic acid (AA) (104)

The transepithelial resistance was then continuously recorded for a further 3 h