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this occurs because there is not enough vitamin B12 in the diet, or poor absorption Pernicious anemiaa type of megaloblastic anemia caused by a lack of intrinsic factor, so that vitamin B12 is not absorbed Fatigue, weakness Nerve damage with numbness, tingling in the hands and legs Memory loss, confusion Dementia Depression Seizures Up to 15% of the general population has a B12 deficiency

Dispose of materials per institutional and regulatory waste requirements

PHGDH is required for germinal center formation and is a therapeutic target in MYC-driven lymphoma

developed a new series of indole/indazole-piperazine pyrimidine analogs with neuroprotective properties (97)