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Furthermore, in clinical studies, sex differences cannot be completely teased apart from gender differences, which are often closely linked to lifestyle and occupational risk factors that are also associated with the onset of NDDs

A cross-sectional study investigating frequency and features of definitely diagnosed diabetic painful polyneuropathy

Molen J, Gonzlez-Correa C, Robles-Vera I, et al

Given the close collaboration between astrocytes and neurons in energy metabolism [135], it is plausible that lactylation, triggered by the accumulation of lactate, may play a supportive role in bolstering neuronal energy metabolism and be a crucial factor in maintaining the metabolic equilibrium necessary for the proper functioning of neural networks