why are my b12 injections not working problems with Do I Feel Worse After B12 Injection? Causes & Management – Best Vitamin B12 Injection Site:

You have difficulty walking or speaking as you used to

In severe cases, a deficiency can even lead to a swollen and inflamed tongue and mouth, known as glossitis

Left untreated, pernicious anemia can cause serious medical issues, including irreversible damage to your nervous system

hospitalization required Maintenance of Remission: Immunomodulators (azathioprine, 6-MP, methotrexate) for steroid-dependent or frequently-relapsing disease Biologic monotherapy or combination therapy (biologic + immunomodulator) for moderate-to-severe disease Step-up or top-down approach based on disease severity, patient risk factors, and prior therapy Biologic Therapy Targets: TNF-: Infliximab (IV), adalimumab (SC), certolizumab pegol (SC) IL-12/23: Ustekinumab (IV induction, SC maintenance) Integrin: Vedolizumab (IV) IL-23: Risankizumab (IV induction, SC maintenance) JAK inhibition: Upadacitinib (oral) Surgical Management Surgery is indicated in approximately 7080% of patients with Crohns disease over their lifetime, per StatPearls