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The theory has the obvious issues of 1) the Terenzis having to make everybody in town (including fellow Officer Dave, who for all Mooney seems to loathe him is quite obviously too law-abiding to do this) agree to prank-call Mooney, 2) everybody in town keeping quiet about this until they execute the plan, 3) everybody in town loathing Mooney that much, 4) that the more realistic calls for help about crazies in clown make-up assaulting people are also part of the prank calls and 5) Dave is willing to risk his own badge alongside Mooney's when he calls Mooney and asks him to call for backup next town over, considering the cops over there won't take being prank-called lightly (and if somehow Dave convinced the cops from the surrounding towns to be part of the prank they also fit the previous points)

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After detailed inspection through Next-Generation Sequencing (NGS), we evaluated the affinity and selectivity of each selected aptamer with integrative molecular approaches, including Dot Blot analysis, biolayer interferometry (BLI) and surface plasmon resonance (SPR)