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Underlying the complex interplay between depression and neuroinflammation is a bidirectional relationship in which depression can induce a neuroinflammatory state, leading to impairments in brain function that can further exacerbate mood disorders

Recovery is typically complete by week 1 (longer if severely ill)

Idebenone, a short-chain coenzyme Q10 homologue, has initially been reported to be effective (at a dosage of 5 to 20 mg/kg/day) in preventing cardiac hypertrophy in most patients [59], while having (at this dosage) little or no effect on the neurological abnormalities [19]

Peng X, Zhou C, Hou X, Liu Y, Wang Z, Peng X, et al