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Sivamani 2010)

Federman DG, Froelich CW, Kirshner RS

Hyperinsulinemia leads to uncoupled insulin regulation of the GLUT4 glucose transporter and the FoxO1 transcription factor

Metabolic abnormalities yield menstrual disorders and ovulatory infertility via perturbed feedback cycles, persistently elevated low-grade inflammation, and aberrant steroidogenesis