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Lee JY, Baw CK, Gupta S, Aziz N, Agarwal A: Role of Oxidative Stress in Polycystic Ovary Syndrome

The Frontiers authors note that estrogen deficiency itself compromises epithelial barriers, mucosal immunity, and the gut microbiota, and that reduced gastric acidity and frequent use of acid-suppressive drugs further facilitate sensitization to foods and medications