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Pharmacodynamic parameters were also measured and demonstrated that the change in inhibition of platelet aggregation was related to the change in the exposure to clopidogrel active metabolite [see Warnings and Precautions (5.7) and Drug Interactions (7)]

Thus, while the current data, based on the 16S rRNA gene V3-V4 region, points towards the existence of at least six SFB lineages in the human population, a more in-depth analysis, with more substantial 16S rRNA gene sequence and genomic data, should reveal the extent of different SFB species and strains in the human population

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Its inclusion at low therapeutic doses contributes to the formula's overall electrolyte balance and complements the action of magnesium, with which it works in a tightly regulated physiological partnership