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Take Away A vitamin B12 injection is absorbed in the blood within minutes after administration

Tesofensine is a triple monoamine reuptake inhibitor (serotonin, noradrenaline, dopamine) extensively studied in pre-clinical models of appetite regulation, energy expenditure, and central reward pathways

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A reasonable titration schedule might look like this: Week 1: 200mcg once daily Week 2: 300mcg once daily Week 3 onward: 300-500mcg based on response and tolerance Optimizing injection technique Poor injection technique contributes to injection site reactions and potentially to other effects like nausea from anxiety around the process