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All have been in the lower normal range, which may be why there are no concrete recommendations to screen all patients on PPIs

In addition, as mentioned previously that MMP-2 was significantly increased in leiomyoma cells, Curcumae rhizoma was also reported to inhibit the expression of MMP-2 which could also contribute to its use in the treatment of UF ( Curcumae rhizoma was also able to induce apoptosis by decreasing the level of BCL-2 and at the same time inhibit the phosphorylation of the AKT/NF-B pathway ( When both of these herbs are used together (known as CRSR, CR:SR = 1:1) in the treatment of UF, the uterine mass was found to be decreased significantly with a significantly lowered progesterone and estradiol level

Intravenous NAC is the standard of care, providing cysteine to regenerate glutathione (Smilkstein et al., N Engl J Med, 1988) [32]

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