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Compound 1c and DRF were orally dosed at 350 mol/kg/day

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Very little progress has been made toward understanding the metabolism of this pathway as labeling experiments in Chimaphila umbellata (pipsissewa) established that tyrosine 132 and DMAPP derived from the MVA pathway 133 provide precursors for chimaphilin (2,7-dimethyl-1,4-NQ

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