mitochondrial glutathione regulation and functions Pleiotropic effects of a mitochondrion-targeted reductase inhibitor on restraining tumor cells Mitochondrial Glutathione: Recent Insights and

All MD simulations were performed with the program package GROMACS (version 2020.4) 32 using the GROMOS 54a7 force field 33

Liposomal Glutathione, on the other hand, uses phospholipid nano-spheres to encapsulate glutathione, protecting it from digestive enzymes and allowing direct absorption into the bloodstream

In sum, emodin emerges as a multi-dimensional agent that aligns a range of cell death pathways (necroptosis, autophagy, and ferroptosis) with immune reprogramming to thwart tumor progression and metastasis

Aptamers are thermostable and chemically stable, and chemical modification can enable their conjugation to nanoparticles, drugs, or other nucleic acid drugs to improve cellular uptake