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Use must comply with all applicable laws, regulations, and laboratory safety standards.

Mitochondria as systemic supplements of the cardio-cerebral axis As the central organelles of energy metabolism, mitochondria play a key role as systemic regulatory factors in the highly metabolically active functional axis comprising the heart and brain

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41 However, the genotoxicity of 2-nitrotoluene and 2,6-dinitrotoluene is due to a product of (di)nitrobenzyl alcohol reduction rather than from reduced metabolites and the gut bacteria plays an important role in this toxicity: both 2-nitrotoluene and 2,6-dinitrotoluene are absorbed in the small intestine and metabolised by the liver to 2-nitrobenzyl alcohol and 2,6-dinitrobenzyl alcohol